Handbook of Antimicrobial Resistance

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Description

Anatomy for Diagnostic Imaging, Fourth Edition covers everything trainee radiologists need to know about anatomy shown in the full range of medical imaging, including CT, MR and ultrasound.

It provides an initial traditional anatomical description of each organ or system, followed by the radiological anatomy of that part of the body with labelled imaging examples in all modalities. A series of 'radiology pearls' emphasises clinically and radiologically important points.

This is a comprehensive tool covering all manifestations of antimicrobial resistance, with viral, bacterial, parasitical and fungal resistance each given a dedicated section. The underlining molecular mechanisms, which depend not only on the microbe, but on the specific drug (target), are highly diverse, and are covered in great detail. This work also discusses and compares the biological, biochemical and structural aspects of resistance and its evolution.

Table of contents (24 entries)

Front Matter

Pages i-xvii

 

Virology

Front Matter

Pages 1-1

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HBV Therapy and the Problem of Drug Resistance

A. J. Thompson, S. A. Locarnini

Pages 3-20

Protease Inhibitor Resistance

Johannes Vermehren, Christoph Welsch, Christoph Sarrazin

Pages 21-40

Contribution of APOBEC3-Driven Mutagenesis to HIV Evolution and HIV Drug Resistance

Marsha Dillon-White, Viviana Simon

Pages 41-57

Resistance to Cyclophilin Inhibitors

Philippe Gallay

Pages 59-85

Antiviral Drug Resistance in Herpesviruses

Jocelyne Piret, Emilien Drouot, Guy Boivin

Pages 87-122

Quasispecies and Drug Resistance

Celia Perales, Ana M. Ortega-Prieto, Nathan M. Beach, Julie Sheldon, Luis Menéndez-Arias, Esteban Domingo

Pages 123-147

Substrate-Envelope-Guided Design of Drugs with a High Barrier to the Evolution of Resistance

Ayşegül Özen, Celia A. Schiffer

Pages 149-173

Bacteriology

Front Matter

Pages 175-175

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The Mechanisms of Resistance to β-Lactam Antibiotics

Dustin T. King, Solmaz Sobhanifar, Natalie C. J. Strynadka

Pages 177-201

Antibiotic Resistance and Tolerance in Bacterial Biofilms

Geoffrey McKay, Dao Nguyen

Pages 203-229

Strategies for Circumventing Bacterial Resistance Mechanisms

Jed F. Fisher, Jarrod W. Johnson, Shahriar Mobashery

Pages 231-261

Drug-Resistant Tuberculosis

Faiz Ahmad Khan, Greg Fox, Dick Menzies

Pages 263-286

Parasitology

Front Matter

Pages 287-287

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The Biochemistry of Quinoline Antimalarial Drug Resistance

Paul S. Callaghan, Paul D. Roepe

Pages 289-311

Drug Resistance in Leishmania

Danielle Légaré, Marc Ouellette

Pages 313-341

Mycology

Front Matter

Pages 343-343

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Microevolution of Antifungal Drug Resistance

Leah E. Cowen

Pages 345-368

The Role of Biofilm Matrix in Mediating Antifungal Resistance

Jeniel E. Nett, David Andes

Pages 369-384

Mycology

Use of Novel Tools to Probe Drug Resistance in Fungi

Yanan Zhao, David S. Perlin

Pages 385-401

Azole Resistance in Aspergillus fumigatus: Mechanisms, Route of Resistance Selection, and Clinical Implications

Seyedmojtaba Seyedmousavi, Paul E. Verweij

Pages 403-421

The Ins and Outs of Azole Antifungal Drug Resistance: Molecular Mechanisms of Transport

Martin Zavrel, Brooke D. Esquivel, Theodore C. White

Pages 423-452

HIV

Front Matter

Pages 453-453

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Transmission of HIV-1 Drug Resistance

Laura Marije Hofstra, Jean-Claude Schmit, Annemarie M. J. Wensing

Pages 455-478

HIV-1 Drug Resistance in Pre-exposure Prophylaxis Trials

Teri Liegler, Robert Grant

Pages 479-498

HIV-1 Entry Inhibitor Resistance

Victor G. Kramer, Mark A. Wainberg

Pages 499-521

HIV-1 Resistance to Reverse Transcriptase Inhibitors

Grant Schauer, Nicolas Sluis-Cremer

Pages 523-542

HIV Drug Resistance in Mothers and Infants Following Use of Antiretrovirals to Prevent Mother-to-Child Transmission

Scott Olson, Quy Ton, Lisa Frenkel

Pages 543-565

HIV Protease Inhibitor Resistance

Annemarie M. J. Wensing, Axel Fun, Monique Nijhuis

Pages 567-602

Back Matter

Pages 603-606


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